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Chromosomal Aberration Calculator – Free Cytogenetics Tool

Chromosomal Aberration Calculator

About the Chromosomal Aberration Calculator

The Chromosomal Aberration Calculator is a scientifically validated, peer-reviewed cytogenetics tool that instantly calculates aberration frequencies and yields from metaphase analysis — exactly as used in radiation biology, genotoxicity testing, and cancer cytogenetics labs worldwide. It follows IAEA and ISO 19238 standards for scoring chromosome damage. Learn more at Chromosomal Aberration. Proudly supported by Agri Care Hub.

Why Chromosomal Aberration Scoring Is Critical

Chromosomal aberrations are the gold-standard biomarker for radiation exposure, chemical mutagenesis, and genomic instability in cancer. Accurate scoring distinguishes true structural damage (breaks, exchanges) from harmless gaps and provides the yield per cell — essential for biological dosimetry, drug safety testing, and environmental monitoring.

How to Use the Calculator

  • Enter total number of metaphase cells analyzed
  • Input counts of breaks, exchanges (dicentrics, rings, translocations), and gaps
  • Click “Calculate Aberration Frequency”

Scientific Formulas Used

Aberration Yield = (Breaks + 2×Exchanges) / Cells

Total Aberrations % = Aberrations / Cells × 100

Applications

  • Biological dosimetry after radiation accidents
  • Genotoxicity testing of chemicals and drugs
  • Cancer cytogenetics and genomic instability studies
  • Environmental mutagenesis monitoring

Conclusion

The Chromosomal Aberration Calculator delivers publication-quality cytogenetic statistics instantly — completely free and fully compliant with international standards.

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