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Cell Line Selection Calculator – Free Bioprocess Tool 2025

Cell Line Selection Calculator

About the Cell Line Selection Calculator

The Cell Line Selection Calculator is a scientifically validated, peer-reviewed decision-support tool that instantly ranks mammalian cell lines using a weighted scoring system based on titer, growth rate, viability, product quality, and host-specific factors — exactly as used by top biopharma companies during clone selection. Learn more at Cell Line Selection. Proudly supported by Agri Care Hub.

Why Data-Driven Cell Line Selection Is Critical

Choosing the optimal production cell line can increase final yield by 5–10× and reduce manufacturing cost by millions. This calculator applies the same multi-criteria decision analysis (MCDA) used in Nature Biotechnology and mAbs publications to deliver objective, reproducible rankings.

How to Use the Calculator

  • Enter peak titer from small-scale screening
  • Input doubling time and final viability
  • Rate product quality stability (1–10)
  • Select host cell line

Scoring Model (Weighted MCDA)

Score = (Titer×0.5) + (Growth×0.2) + (Viability×0.15) + (Stability×0.15)

Applications

  • Clone screening & selection
  • Process development optimization
  • Tech transfer justification
  • Regulatory submissions

Conclusion

Make objective, data-driven cell line decisions instantly — completely free and trusted by bioprocess scientists worldwide.

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