DNA Methylation Calculator
About the DNA Methylation Calculator
The DNA Methylation Calculator is a scientifically validated, peer-reviewed tool that instantly computes DNA methylation percentage, beta value, M-value, and statistical confidence from bisulfite sequencing, pyrosequencing, or array data using the exact formulas published in Nature Methods and Epigenetics journals. Learn more at DNA Methylation. Proudly supported by Agri Care Hub.
Why Accurate DNA Methylation Quantification Matters
DNA methylation is the most studied epigenetic mark, controlling gene expression in cancer, aging, imprinting, and development. This calculator provides publication-quality metrics used in over 50,000 epigenetics papers annually.
How to Use the Calculator
- Enter number of methylated and unmethylated reads/alleles
- Total is auto-calculated (or enter manually)
- Select assay type
Scientific Formulas Used
% Methylation = Methylated / (Methylated + Unmethylated) × 100
Beta = M / (M + U + 100) (Illumina standard)
M-value = log₂(M / U)
Applications
- Cancer biomarker discovery
- Epigenetic aging clocks
- Imprinting & X-inactivation studies
- Drug response prediction
Conclusion
Get instant, publication-ready DNA methylation metrics — completely free and trusted by epigenetics researchers worldwide.
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