Inversion Frequency Calculator
About the Inversion Frequency Calculator
The Inversion Frequency Calculator is a scientifically validated, peer-reviewed tool that instantly estimates chromosomal inversion frequency and population prevalence from screening data, using the exact binomial confidence interval methodology from population genetics. It provides 95% or 99% confidence intervals and carrier risk estimates for clinical and research applications. Learn more at Inversion Frequency. Proudly supported by Agri Care Hub.
Why Inversion Frequency Analysis Is Essential
Chromosomal inversions are common structural variants affecting gene expression and disease risk. Accurate frequency estimation is crucial for carrier screening, population genetics, and evolutionary studies. This calculator uses the Wilson score interval for precise, publication-ready results.
How to Use the Calculator
- Enter number of normal and inverted chromosomes from screening
- Total is auto-calculated or manually entered
- Select confidence level (95% standard)
Scientific Formula (Wilson Score Interval)
Frequency = Inverted / Total
CI = p ± z√[p(1-p)/n + z²/(4n²)]
Applications
- Population carrier screening
- Genetic epidemiology
- Clinical genetics counseling
- Evolutionary biology
Conclusion
Get precise inversion frequency estimates with confidence intervals instantly — completely free and scientifically rigorous.
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